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INTRODUCTION Major depression also referred to as clinical depression by episodes of persistent sadness, anger, loss of interest in usual activities and little to no interest in relating with others. The complication may be caused by the loss of beloved ones, relationship problem, trauma or any stressful situation (de Sousa et al., 2015). This kind of depression is a major disorder that reoccurs affecting 10% 15 % of the worlds total population. Many improvements have been made in the psychopharmacology of major depression as well as the use of different anti-depressants. However, only 60 to 70 percent of the individuals diagnosed with major depression show responses to antidepressant therapy (Li et al., 2017). Approximately...